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POW-Down is a status ailment that has appeared in various RPGs. It stands for "Power-Down".
Mario & Luigi series
Mario & Luigi: Superstar Saga
In Mario & Luigi: Superstar Saga, some enemies have the ability to change the Mario brothers' stats. If their attack power goes down, they won't be able to do as much damage with their attacks. The ailment is indicated by a red burst with an arrow pointing down.
Starkisses are one of the enemies that can cause POW-Down to the Mario bros.
Mario & Luigi: Partners in Time
Mario & Luigi: Bowser's Inside Story
Paper Mario series
Paper Mario: The Thousand-Year Door
In Paper Mario: The Thousand-Year Door, Mario can once again inflict the Tiny status effect by using Shrink Stomp. Yoshi can also do this by using Mini-Egg, and the item Mini Mr. Mini can shrink enemies as well.