From the Super Mario Wiki
Bowser's Inside Story + Bowser Jr's Journey Enemy
Location(s): Nerve Cluster
Level: 7
HP: 10
POW: 18
DEF: 14
Experience: 0
Coins: 0
Item Drop: Syrup Jar - 30%
Nut - 10%
Fire: Critical
Jump: Normal
Hammer: Normal
Battled by: Mario & Luigi
Burn: 2x
Dizzy: 1x
Stat Down: 1x
Speed down: 1x
Bowser's Inside Story Enemy
M&LBIS Biffidus.png
Location(s) Nerve Cluster
Battled by Mario and Luigi
Level 7
HP 10 (15)
POW 18 (45)
DEF 16 (24)
SPEED 50 (75)
Fire Double
Burn? Normal
Dizzy? Normal
Stat Down? Normal
KO? Immune
Experience 0
Coins 0 (0)
Item Drop Syrup Jar - 5%
  • The second set of numbers next to the enemy's HP, POW, DEF, SPEED and Coins are stat increases from the Challenge Medal accessory; a 50% increase for HP, DEF, SPEED and Coins earned, and a 150% increase for POW.

The Biffidus is a member of a tribe-like group of Biffidus, who act as antibodies within Bowser's body, and appear to assist the parasite worm Durmite. They have round white bodies with black faces and featureless eyes. They also have red feet, and they carry shields and spears. During the events of Mario & Luigi: Bowser's Inside Story, Bowser ate a huge carrot which, unknown to him at the time, contained Durmite. The Biffidus assist Durmite in battle by trying to jab Mario or Luigi with their spears. However, after taking much damage, Durmite will eat the Biffidus, then regurgitate their spears at Mario or Luigi, which they must jump over. In the battle with Durmite X, Biffidus Xs appear instead of regular Biffiduses.

Names in other languages[edit]

Language Name Meaning
Japanese ビフィーズ人
Bifīzu Jin
Possibly from bifizusu, the Japanese name for the bifidobacteria. They are the only enemy in the game to have a kanji in their name during battle. Other enemies with a kanji name revert to hiragana during battle.
Spanish (NOA) Enzimo From enzima that means enzyme
Spanish (NOE) Bífido Biffidus
French (NOE) Bifigus From bifidus and gus or gugusse, a slang word equivalent to gizmo.
German Oxygardist From Oxygen and "Gardist" which means guard.
Italian Bifidus -