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The RenewaLeaf is an item found in Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey. It is a type of antidote that is capable of removing the effects of the Malatone Formula:X. When Bowser Jr. visits Dimble Wood for the second time and defeats Kaley for the first time, Ludwig gives him the leaf so they can help cure those who ingested the Malatone. Much later in Bowser's Castle, the leaf was fed to Morton, who turns back to normal.
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