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Artwork of an Emoglobin
First appearance Mario & Luigi: Bowser's Inside Story (2009)
Latest appearance Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey (2018)
Derived species
“Go. Be globin.”
Emoglobin, Mario & Luigi: Bowser's Inside Story

Emoglobins are block-like creatures that appear inside Bowser's body in Mario & Luigi: Bowser's Inside Story. They often are helpful, explaining to Mario and Luigi about how Bowser's body works. There are also rarer kinds that allow the brothers to save their game. They are usually orange or yellow, and Mario or Luigi must jump to hit and talk with them. There are usually a few Emoglobins found in each part of Bowser's body. They are known for replacing random nouns with the word "globin" (e.g. It's not globin science), and often putting "-ish" at the end of adjectives. In the European Spanish translation they speak in a poem-like way in a very refined Spanish with rhymes.

There are also special Emoglobins located in the Toad Square and the Trash Pit. They are colored orange with green eyes. This type of globin secretes a sweat that restores both the HP and SP of Mario and Luigi. A Toad runs a shop in Toad Square and sells the sweat for 10 coins, while the other is free to use.

There is also a kind of Emoglobin in the Challenge Node that resembles a Nintendo DS. The one who manages the Gauntlet can transform into bosses that the Bros. have encountered earlier in the game.


  • Evoglobin - Mystical parts of Bowser's soul.
  • Nutsoglobin - Emoglobins who like to quiz the Mario Bros. about Bowser.
  • Liftoglobin - Nonverbal Emoglobins who can be used as moving platforms.
  • Totemglobin - A tower of Emoglobins that have the Mario Bros. play their game before letting them pass.

Names in other languages[edit]

Language Name Meaning
Japanese ヘモグロびん
From the oxygen-carrying protein hemoglobin.
Spanish (NOA) Emoglobín Emoglobin
Spanish (NOE) Infoglobina Infoglobin, also, in this translation, the Emoglobins were female.
French (NOA) Emoglobine From "hémoglobine" (hemoglobin)
French (NOE) Hémoglobing From "hémoglobine" (hemoglobin) and the fact they frequently says "bing".
German Hämoglobin Hemoglobin
Korean 헬로글로빈


  • Their name is a pun on the word hemoglobin, which is contained in the red blood cells of vertebrates.