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Artwork of an Emoglobin
First appearance Mario & Luigi: Bowser's Inside Story (2009)
Latest appearance Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey (2018)
“Go. Be globin.”
Emoglobin, Mario & Luigi: Bowser's Inside Story

Emoglobins are block-like creatures that appear inside Bowser's body in Mario & Luigi: Bowser's Inside Story. Their name is a pun on hemoglobin, an iron-rich protein in the red blood cells of vertebrates that aids in the transportation of oxygen.

They often are helpful, explaining to Mario and Luigi about how Bowser's body works. There are also rarer kinds that allow the brothers to save their game, like in the Rump Command. They are usually orange or yellow, and Mario or Luigi must jump to hit and talk with them. There are usually a few Emoglobins found in each part of Bowser's body. They are known for replacing random nouns with the word "globin" (e.g. It's not globin science), and often putting "-ish" at the end of adjectives. In the Castilian Spanish translation they speak in a poem-like way in a very refined Spanish with rhymes.

There are also special Emoglobins located in the Toad Square and the Trash Pit. They are colored orange with green eyes. This type of globin secretes a sweat that restores both Mario and Luigi's HP and SP, similar to Recovery Blocks. A Toad runs a shop in Toad Square and sells the sweat for 10 coins, while the other is free to use.

There is also a kind of Emoglobin in the Challenge Node that resembles a Nintendo DS. The one who manages the Gauntlet uses the Bros.' memories to create stronger versions of the bosses that the Bros. have encountered through the game, and allows Mario and Luigi to fight these "X" bosses for a sizable fee.


  • Evoglobin - Mystical parts of Bowser's soul.
  • Nutsoglobin - Emoglobins who like to quiz the Mario Bros. about Bowser.
  • Liftoglobin - Nonverbal Emoglobins who can be used as moving platforms.
  • Totemglobin - A tower of Emoglobins in the Airway that have the Mario Bros. play their game before letting them pass.

Names in other languages[edit]

Language Name Meaning
Japanese ヘモグロびん
From "hemoglobin", the oxygen-carrying protein

French (NOA) Emoglobine
From "hémoglobine" (hemoglobin)
French (NOE) Hémoglobing
From "hémoglobine" (hemoglobin) and the fact they frequently says "bing".
German Hämoglobin
Korean 헬로글로빈

Spanish (NOA) Emoglobín
Spanish (NOE) Infoglobina
Infoglobin, also, in this translation, the Emoglobins were female.