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The Prado Museum is a national art museum, housing countless exhibits in Madrid. In the DOS and Deluxe versions of Mario is Missing!, it is one of the city's landmarks (alongside the Palacio de las Cortes and the Ventas Bullring) that gets ransacked by Koopa Troopas. They steal one of the museums's paintings, Guernica by Pablo Picasso, causing the entire museum to shut down; they also place a bounty on its return. Luigi promptly does just that: he retrieves the painting, and after proving that it is real by answer the questions listed below, it is returned to its rightful place.
Picasso's painting, Guernica, hangs in the world famous Prado Museum. Pablo Ruiz Picasso was born in Malaga, Spain in 1881. When he died in 1973, he was known as the greatest figure in modern Spanish art. Although he lived in France most of his life, Spain is eager to claim Picasso as a native son. The 1937 bombing of the town, Guernica, during the Spanish civil war inspired Picasso's most famous painting, Guernica. Like the artist, the painting was outside Spain for years. It was finally brought home to the Prado Museum in 1981.