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The Mona Lisa is a famous painting featured in the SNES version of Mario's Time Machine. It was painted by Leonardo da Vinci in the year 1505, and it is a portrait of Lady Giocondo (noted by Michelangelo Buonarroti as having a captivating smile). When Leonardo is first met, he refuses to talk, as he has lost his Notebook (which was stolen by a time-travelling Bowser) and he is unable to complete the painting without it. After Mario returns Leonardo's Notebook to him, he exclaims his thanks, saying that he is now able to finish painting the Mona Lisa. Mario then asks why the Mona Lisa isn't smiling, to which Leonardo responds that she actually has a subtle smile, one that makes future generations wonder what she is smiling about.