From the Super Mario Wiki, the Mario encyclopedia
Artwork of a Megavitamin from Dr. Mario World.
A capsule like object with two colors; either the same or different.

First appearance

Dr. Mario (1990)

Latest appearance

Dr. Kawashima's Brain Training for Nintendo Switch (2019)
Dr. Mario World (2019, Mario franchise)

Effect on player

Defeats a virus of the same color when four (or three in Dr. Mario World) are piled up.
Dr. Mario juggling three Megavitamins

Megavitamins, also known as capsules, are Dr. Mario's prescription of choice, seen in the Dr. Mario series. Invented by Dr. Mario himself,[1] Megavitamins are an effective weapon against both viruses and the flu.[2]

They come in six different color combinations that include red, blue, or yellow (all red, all blue, all yellow, red and blue, yellow and blue, and red and yellow). For the Game Boy version, these patterns correspond to black, white, and gray/textured colors. Dr. Mario uses the Megavitamins to destroy viruses, in the game Dr. Mario.

In Super Smash Bros. Melee, Super Smash Bros. for Nintendo 3DS / Wii U, and Super Smash Bros. Ultimate, Dr. Mario's standard special is Megavitamins, in which Dr. Mario tosses a Megavitamin at opponents. They act the same as Mario's Fireball move, except that the Megavitamins are more powerful. They also bounce in a different path, and make a different noise when it hits. There's also a trophy of Dr. Mario shooting Megavitamins and one of the vitamins themselves. Kirby is also able to use the Megavitamins if he copies Dr. Mario, although the sound that plays when the Megavitamin hits an opponent is different. Like in the Dr. Mario games, the Megavitamins are randomly generated with different color combinations, though this has no effect on the attack itself. Super Smash Bros. for Nintendo 3DS / Wii U also gives this move two customizable variants, which are similar in effect to Mario's Fireball customs. The first is Fast Capsule, which sends out a fast-moving but weaker Megavitamin that travels directly forward, and the second is Mega Capsule, which sends out a slow-moving giant Megavitamin that does not travel as far but deals multiple hits of damage.

In Super Smash Bros. Brawl, a Megavitamin appears as a sticker, which boosts the attack of the equipped character by five points.

In Dr. Mario 64, Megavitamins also seem to have a transforming property; when Dr. Mario or Wario eats them, they transform into Metal Mario and Vampire Wario, respectively.

In WarioWare, Inc.: Mega Microgame$!, a minigame called Dr. Wario features Wario in a doctor persona using Megavitamins to eliminate viruses. In addition, starting with Dr. Luigi, Luigi's doctor persona also uses Megavitamins to eliminate viruses. Also starting with Dr. Luigi, L-shaped Megavitamins have been used.

In Super Mario Maker, when playing as Dr. Mario's costume, holding the +Control Pad up button will result in Dr. Mario holding up a Megavitamin.



Super Smash Bros. Melee trophy[edit]

Name Image Game Description
Megavitamins Trophy155.png Dr. Mario
Megavitamins come in six color combinations of red, blue, and yellow. Dr. Mario uses these capsules by tossing them into contaminated bottle to destroy viruses. The origin of these wonder pills is a mystery, but the most likely theory is that they're the result of Dr. Mario's lifelong efforts to find a cure for the common cold.

Super Smash Bros. Brawl sticker[edit]

Name Image Artwork from Effect in The Subspace Emissary
Capsule Capsule Sticker.png Nintendo Puzzle Collection [Flame] - Attack +5

Names in other languages[edit]

Language Name Meaning
Japanese カプセル
Chinese (Simplified) 大剂量维生素[3] (Dr. Mario 64)
Dàjìliàng Wéishēngsù
药丸[4] (Dr. Mario Express)
胶囊 (Dr. Mario World)



Chinese (Traditional) 膠囊



  1. ^ "I have just developed a new vitamin that should be able to take care of it. I sure hope this stuff works!" - Dr. Mario NES instruction booklet, page 3.
  2. ^ "Flu season has struck! Now Dr. Mario, armed with his mighty Megavitamins, is busier than ever treating patients." - Dr. Mario 64 instruction booklet, page 13.
  3. ^ Official Chinese website for Dr. Mario 64. Retrieved April 5, 2020.
  4. ^
Megavitamin's page on other NIWA wikis: