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| Dr. Mario 64
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For alternate box art, see the game's gallery.
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| Developer
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Nintendo (division unknown)
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| Publisher
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Nintendo
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| Platforms
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Nintendo 64, iQue Player, Nintendo GameCube, Nintendo 64 - Nintendo Switch Online
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| Release date
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Original:
 April 9, 2001
 November 17, 2003 (iQue Player)
Nintendo GameCube:
 February 7, 2003
Nintendo 64 - Nintendo Switch Online:
October 2021[1]
 October 2021[2]
 October 2021[3]
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| Genre
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Puzzle
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| Rating(s)
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| Mode(s)
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Single-player, Multiplayer
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| Media
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Nintendo 64:
 Game Pak iQue Player:
 Digital download GameCube:
 Optical disc |
| Input
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Nintendo 64: iQue Player: GameCube:
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Dr. Mario 64 is a puzzle game developed by Nintendo and released for the Nintendo 64. This is the third installment in the Dr. Mario series and the final Mario game released for the Nintendo 64. In 2003, it was re-released along with Panel de Pon and Yoshi's Cookie in a Japan-only Nintendo GameCube game called Nintendo Puzzle Collection. In 2005, Dr. Mario & Puzzle League was released, with the Dr. Mario portion mostly taking visual and audio cues from the N64 version. The original game will be made available on Nintendo 64 - Nintendo Switch Online in North America, Europe, and Australia as one of its launch titles, marking its first release in the last two regions.
Gameplay[edit]
 A screenshot from Dr. Mario 64. Dr. Mario 64 plays the same as its predecessors for the most part. Dr. Mario throws Megavitamins into a jar full of Viruses, and the goal is to line up a minimum of four of a color combination of Viruses and Megavitamins to make them disappear. There are three types of Viruses - the Red Virus (Fever), the Blue Virus (Chill) and the Yellow Virus (Weird), with a Megavitamin color designed to defeat them.
Dr. Mario 64 features many different modes of play (all of which have tutorials hosted by a Para-Goom). The player uses the  to toggle with the different modes they wish to select. The first one is Classic mode, where Dr. Mario is playable like he was originally. In the second mode of play, Story mode, Dr. Mario or Wario must track down the stolen Megavitamins. This mode only has versus matches against computers. The third mode allows practice against a computer player, where any character found in Story mode can be selected. The fourth game mode is Flash mode, where only the clearing of flashing Viruses counts. The fifth game mode is Marathon mode, which is basically an endless mode (the Viruses never stop coming out of the bottom of the jar). The sixth game mode is Score Attack mode, where there are only three minutes to get both a high score and clear all of the viruses. Multiplayer mode supports up to four players, which adds a mode allowing four players to play on two teams.
Dr. Mario's story[edit]
Unlike past Dr. Mario games, this game has a storyline. It is flu season and Dr. Mario is using his Megavitamins to heal the infirmities of the citizens of the land. However, Wario attempts to steal the Megavitamins, believing that if he has them, he will be rich. Before he can do so, Mad Scienstein takes the Megavitamins. Dr. Mario chases Wario, believing he has the Megavitamins, and they duel. Afterwards, they both go after Mad Scienstein. Throughout their adventure they both meet many creatures, all of them villains from Wario Land 3. In the end, it is revealed that Mad Scienstein stole the Megavitamins for the diabolical Rudy, who wishes to cure his cold. Dr. Mario defeats Rudy, takes back his trusty Megavitamins, and makes Rudy happy by curing his cold. If Dr. Mario has not lost any matches, Wario will take the Megavitamins and consume all of them at once, transforming him into Vampire Wario.
Enemies exclusive to Dr. Mario's story[edit]
- Wario
- Silky
- Jellybob
- Helio
- Vampire Wario
Wario's story[edit]
Wario's story is slightly different in that his story features enemies that Dr. Mario does not face. In his ending, he defeats Rudy, but then Mad Scienstein comes and runs off with the Megavitamins. Wario runs after him and the chase continues, seemingly with no end. If Wario has not lost any matches, Dr. Mario will try to get the Megavitamins back. Wario will rush away, but he will trip, causing the Megavitamins to spill out of the jar and onto Dr. Mario. Dr. Mario will swallow all of them and transform into Metal Mario. Since Wario is the playable character in this mode, his role as an opponent is switched with Dr. Mario.
Enemies exclusive to Wario's story[edit]
- Dr. Mario
- Appleby
- Lump
- Octo
- Metal Mario
Playable characters[edit]
The default cast of characters. The final cast of characters.
Reception[edit]
Overall, Dr. Mario 64 received mostly positive reviews. GameRankings gave the game a score of 70.03%, while Metacritic gave it a score of 71/100. GameSpot also gave the game a 7.0/10. Dr. Mario 64 was voted #76 in the Top 100 Games of All Time poll published by Game Informer Magazine in August 2001.
| Reviews
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| Release
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Reviewer, Publication
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Score
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Comment
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| N64
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Gerald Villoria, GameSpot
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7/10
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"While not as exciting or enduring as Nintendo's last puzzle game, The New Tetris, Dr. Mario is a legitimate and satisfying puzzle game that is executed rather nicely in this four-player-focused package. Nintendo has made the decision to value-price Dr. Mario 64 at $29.95, which--along with the excellent multiplayer format--makes it worthwhile as one of the last N64 games to be released."
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| N64
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Fran Mirabella III, IGN
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5/10
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"To be honest, Dr. Mario 64 is just about everything I expected it to be. It was obviously an effort by Nintendo to get a game out for the month of April, and get it out quickly. There have been virtually zero upgrades outside of the four-player versus modes, which lends little reason not to go back and play SNES version which featured both Dr. Mario and Tetris. If you're dying for a multiplayer puzzle game that you can play with three friends, then Dr. Mario 64 is well worth it for around $30. Otherwise, I suggest sticking with The New Tetris or the well Pok¿mon[sic] Puzzle League. Dr. Mario 64 is more or less Nintendo's way of using Mario's name to sell a port of a very old game. This doctor's Ph.D. expired long ago."
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| Aggregators
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| Compiler
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Platform / Score
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| Metacritic
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71
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| GameRankings
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70.03%
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References to other games[edit]
- Dr. Mario - The basic formula for the Dr. Mario series is carried on from this game.
- Super Mario 64 - Power Stars are used as indicators for whenever a character wins a match. When Dr. Mario wins, he spins and puts up a peace sign the way Mario does when he acquires a Power Star in Super Mario 64. Metal Mario (as both a powered-up form of Dr. Mario and a secret unlockable character) is a power-up from this game.
- Wario Land 3 - All characters apart from Dr. Mario, Metal Mario and the Viruses are from this game.
Gallery[edit]
- For this subject's image gallery, see Gallery:Dr. Mario 64.
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It has been suggested that audio and/or video file(s) related to this section be uploaded.
Please upload all related music, sound effects, voice clips, or any videos for this section. See the help page for information on how to get started.
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- Help:Media • Having trouble playing?
Dr. Mario 64 coverage on other NIWA wikis:
- Main article: List of Dr. Mario 64 staff
Hitoshi Yagami, director of the original Dr. Mario, returned to director and game design duties for Dr. Mario 64. The game had a large number of graphic designers and character artists, all of which were professional anime animators with otherwise little to no involvement in the game industry.
References[edit]
- ^ Nintendo (September 23, 2021). Nintendo Direct - 9.23.2021. YouTube. Retrieved September 24, 2021.
- ^ @NintendoEurope (September 23, 2021). "Play a growing library of Nintendo 64 and SEGA Mega Drive games anytime, anywhere with #NintendoSwitchOnline + Expansion Pack, a new membership launching in late October." Twitter. Retrieved September 24, 2021.
- ^ @NintendoAUNZ (September 24, 2021). "Play a growing library of Nintendo 64 and SEGA Mega Drive games anytime, anywhere with #NintendoSwitchOnline + Expansion Pack, a new membership launching in late October." Twitter. Retrieved September 24, 2021.
| Mario games
|
| Platformers
|
Super Mario series
|
Super Mario Bros. (1985, NES) • Super Mario Bros.: The Lost Levels (1986, FDS) • Super Mario Bros. 2 (1988, NES) • Super Mario Bros. 3 (1988, NES) • Super Mario Land (1989, GB) • Super Mario World (1990, SNES) • Super Mario Land 2: 6 Golden Coins (1992, GB) • Super Mario 64 (1996, N64) • Super Mario Sunshine (2002, GCN) • New Super Mario Bros. (2006, NDS) • Super Mario Galaxy (2007, Wii) • New Super Mario Bros. Wii (2009, Wii) • Super Mario Galaxy 2 (2010, Wii) • Super Mario 3D Land (2011, 3DS) • New Super Mario Bros. 2 (2012, 3DS) • New Super Mario Bros. U (2012, Wii U) • Super Mario 3D World (2013, Wii U) • Super Mario Maker (2015, Wii U) • Super Mario Run (2016, iOS/Android) • Super Mario Odyssey (2017, NS) • Super Mario Maker 2 (2019, NS)
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| Mario vs. Donkey Kong series
|
Mario vs. Donkey Kong (2004, GBA) • Mario vs. Donkey Kong 2: March of the Minis (2006, DS) • Mario vs. Donkey Kong: Minis March Again! (2009, DSiWare) • Mario vs. Donkey Kong: Mini-Land Mayhem! (2010, DS) • Mario and Donkey Kong: Minis on the Move (2013, 3DS) • Mario vs. Donkey Kong: Tipping Stars (2015, 3DS/Wii U) • Mini Mario & Friends: amiibo Challenge (2016, 3DS/Wii U)
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| Other
|
Donkey Kong (1981, Arcade) • Mario Bros. (1983, G&W) • Mario's Cement Factory (1983, G&W) • Mario Bros. (1983, Arcade) • VS. Wrecking Crew (1984, Arcade) • Mario Bros. Special (1984, PC) • Punch Ball Mario Bros. (1984, PC) • Wrecking Crew (1985, NES) • Super Mario Bros. Special (1986, PC) • Mario & Wario (1993, SNES) • Hotel Mario (1994, Philips CD-i) • Donkey Kong (1994, Game Boy) • Mario Clash (1995, VB) • Wrecking Crew '98 (1998, SFC) • Super Princess Peach (2005, DS) • New Super Luigi U (2013, Wii U) • Captain Toad: Treasure Tracker (2014, Wii U) • Super Mario Bros. 35 (2020, NS)
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| Ports and remakes
|
Crazy Kong (1981, Arcade) • Donkey Kong (1982, G&W) • VS. Super Mario Bros. (1986, Arcade) • Super Mario Bros. (1986, G&W) • All Night Nippon Super Mario Bros. (1986, FDS) • Kaettekita Mario Bros. (1988, FDS) • Super Mario All-Stars (1993, SNES) • Super Mario All-Stars + Super Mario World (1994, SNES) • BS Super Mario USA (1996, SNES) • BS Super Mario Collection (1997, SNES) • Super Mario Bros. Deluxe (1999, GBC) • Super Mario Advance (2001, GBA) • Super Mario World: Super Mario Advance 2 (2002, GBA) • Super Mario Advance 4: Super Mario Bros. 3 (2003, GBA) • Famicom Mini Series (2004, GBA) • Classic NES Series (2004-2005, GBA) • Super Mario 64 DS (2004, NDS) • Virtual Console (2006-current, Wii/3DS/Wii U) • Super Mario All-Stars Limited Edition (2010, Wii) • Luigi Bros. (2013, Wii U) • Super Mario Maker for Nintendo 3DS (2016, 3DS) • Captain Toad: Treasure Tracker (2018, NS/3DS) • New Super Mario Bros. U Deluxe (2019, NS) • Super Mario 3D All-Stars (2020, NS) • Game & Watch: Super Mario Bros. (2020, G&W) • Super Mario 3D World + Bowser's Fury (2021, NS)
|
| Role-playing games
|
Paper Mario series
|
Paper Mario (2000, N64) • Paper Mario: The Thousand-Year Door (2004, GCN) • Super Paper Mario (2007, Wii) • Paper Mario: Sticker Star (2012, 3DS) • Paper Mario: Color Splash (2016, Wii U) • Paper Mario: The Origami King (2020, NS)
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| Mario & Luigi series
|
Mario & Luigi: Superstar Saga (2003, GBA) • Mario & Luigi: Partners in Time (2005, NDS) • Mario & Luigi: Bowser's Inside Story (2009, NDS) • Mario & Luigi: Dream Team (2013, 3DS) • Mario & Luigi: Paper Jam (2015, 3DS)
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| Other
|
Super Mario RPG: Legend of the Seven Stars (1996, SNES)
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| Remakes
|
Mario & Luigi: Superstar Saga + Bowser's Minions (2017, 3DS) • Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey (2018, 3DS)
|
| Dr. Mario series
|
Main
|
Dr. Mario (1990, NES) • Dr. Mario 64 (2001, N64) • Dr. Mario Online Rx (2008, WiiWare) • Dr. Mario Express (2008, DSiWare) • Dr. Luigi (2013, Wii U) • Dr. Mario: Miracle Cure (2015, 3DS) • Dr. Mario World (2019, iOS/Android)
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| Other
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VS. Dr. Mario (1990, Arcade)
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| Remakes
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Tetris & Dr. Mario (1994, SNES) • Nintendo Puzzle Collection (2003, GCN) • Dr. Mario & Puzzle League (2005, GBA)
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| Mario Kart series
|
Main
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Super Mario Kart (1992, SNES) • Mario Kart 64 (1996, N64) • Mario Kart: Super Circuit (2001, GBA) • Mario Kart: Double Dash!! (2003, GCN) • Mario Kart DS (2005, NDS) • Mario Kart Wii (2008, Wii) • Mario Kart 7 (2011, 3DS) • Mario Kart 8 (2014, Wii U) • Mario Kart Tour (2019, iOS/Android)
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| Arcade
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Mario Kart Arcade GP (2005, Arcade) • Mario Kart Arcade GP 2 (2007, Arcade) • Mario Kart Arcade GP DX (2013, Arcade) • Mario Kart Arcade GP VR (2017, Arcade)
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| Other
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Mario Kart Live: Home Circuit (2020, NS)
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| Ports
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Mario Kart 8 Deluxe (2017, NS)
|
| Mario Party series
|
Main
|
Mario Party (1998, N64) • Mario Party 2 (1999, N64) • Mario Party 3 (2000, N64) • Mario Party 4 (2002, GCN) • Mario Party 5 (2003, GCN) • Mario Party 6 (2004, GCN) • Mario Party 7 (2005, GCN) • Mario Party 8 (2007, Wii) • Mario Party 9 (2012, Wii) • Mario Party 10 (2015, Wii U) • Super Mario Party (2018, NS)
|
| Arcade
|
Super Mario Fushigi no Korokoro Party (2004, Arcade) • Super Mario Fushigi no Korokoro Party 2 (2005, Arcade) • Mario Party Fushigi no Korokoro Catcher (2009, Arcade) • Mario Party Kurukuru Carnival (2012, Arcade) • Mario Party Fushigi no Korokoro Catcher 2 (2013, Arcade) • Mario Party Challenge World (2016, Arcade)
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| Other
|
Mario Party-e (2003, GBA) • Mario Party Advance (2005, GBA) • Mario Party DS (2007, NDS) • Mario Party: Island Tour (2013, 3DS) • Mario Party: Star Rush (2016, 3DS) • Mario Party: The Top 100 (2017, 3DS) • Mario Party Superstars (2021, NS)
|
| Luigi's Mansion series
|
Main
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Luigi's Mansion (2001, GCN) • Luigi's Mansion: Dark Moon (2013, 3DS) • Luigi's Mansion Arcade (2015, Arcade) • Luigi's Mansion 3 (2019, NS)
|
| Remakes
|
Luigi's Mansion (2018, 3DS)
|
| Sports games
|
Mario Baseball series
|
Mario Superstar Baseball (2005, GCN) • Mario Super Sluggers (2008, Wii)
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| Mario Golf series
|
Golf (1984, NES) • Family Computer Golf: Japan Course (1987, FDS) • Family Computer Golf: U.S. Course (1987, FDS) • NES Open Tournament Golf (1991, NES) • Mario Golf (1999, N64) • Mario Golf (1999, GBC) • Mobile Golf (2001, GBC) • Mario Golf: Toadstool Tour (2003, GCN) • Mario Golf: Advance Tour (2004, GBA) • Mario Golf: World Tour (2014, 3DS) • Mario Golf: Super Rush (2021, NS)
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| Mario Strikers series
|
Super Mario Strikers (2005, GCN) • Mario Strikers Charged (2007, Wii)
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| Mario Tennis series
|
Mario's Tennis (1995, VB) • Mario Tennis (2000, N64) • Mario Tennis (2000, GBC) • Mario Power Tennis (2004, GCN) • Mario Tennis: Power Tour (2005, GBA) • Mario Tennis Open (2012, 3DS) • Mario Tennis: Ultra Smash (2015, Wii U) • Mario Tennis Aces (2018, NS)
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| Ports
|
New Play Control! Mario Power Tennis (2009, Wii)
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| Other
|
Donkey Kong Hockey (1984, G&W) • NBA Street V3 (2005, GCN) • SSX on Tour (2005, GCN) • Mario Hoops 3-on-3 (2006, NDS) • Mario Sports Mix (2010, Wii) • Mario Sports Superstars (2017, 3DS)
|
| Crossovers
|
Mario & Sonic series
|
Mario & Sonic at the Olympic Games (2007, Wii) • Mario & Sonic at the Olympic Games (2008, NDS) • Mario & Sonic at the Olympic Winter Games (2009, Wii) • Mario & Sonic at the Olympic Winter Games (2009, NDS) • Mario & Sonic at the London 2012 Olympic Games (2011, Wii) • Mario & Sonic at the London 2012 Olympic Games (2012, 3DS) • Mario & Sonic at the Sochi 2014 Olympic Winter Games (2013, Wii U) • Mario & Sonic at the Rio 2016 Olympic Games (2016, Wii U) • Mario & Sonic at the Rio 2016 Olympic Games (2016, 3DS) • Mario & Sonic at the Rio 2016 Olympic Games Arcade Edition (2016, Arcade) • Mario & Sonic at the Olympic Games Tokyo 2020 (2019, NS) • Mario & Sonic at the Olympic Games Tokyo 2020 - Arcade Edition (2020, Arcade)
|
| Super Smash Bros. series
|
Super Smash Bros. (1999, N64) • Super Smash Bros. Melee (2001, GCN) • Super Smash Bros. Brawl (2008, Wii) • Super Smash Bros. for Nintendo 3DS (2014, 3DS) • Super Smash Bros. for Wii U (2014, Wii U) • Super Smash Bros. Ultimate (2018, NS)
|
| Mario + Rabbids series
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Mario + Rabbids Kingdom Battle (2017, NS) • Mario + Rabbids Sparks of Hope (2022, NS)
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| Itadaki Street series
|
Itadaki Street DS (2007, NDS) • Fortune Street (2011, Wii)
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| Other
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Nintendo Land (2012, Wii U) • Puzzle & Dragons: Super Mario Bros. Edition (2015, 3DS)
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| Educational games
|
Mario Discovery series
|
Mario is Missing! (1993, MS-DOS/SNES/NES) • Mario's Time Machine (1993, MS-DOS/SNES/NES) • Mario's Early Years! Fun with Letters (1993, MS-DOS/SNES) • Mario's Early Years! Fun with Numbers (1994, MS-DOS/SNES) • Mario's Early Years! Preschool Fun (1994, MS-DOS/SNES)
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| Other
|
Mario Teaches Typing (1991, MS-DOS) • Super Mario Bros. & Friends: When I Grow Up (1991, MS-DOS) • Mario Teaches Typing 2 (1996, MS-DOS)
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| Ports
|
Mario's Early Years! CD-ROM Collection (1995, PC)
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| Art utilities
|
Super Mario Bros. Print World (1991, MS-DOS) • Mario Paint (1992, SNES) • Super Mario Collection Screen Saver (1997, PC) • Mario no Photopi (1998, N64) • Mario Artist: Paint Studio (1999, N64DD) • Mario Artist: Talent Studio (2000, N64DD) • Mario Artist: Communication Kit (2000, N64DD) • Mario Artist: Polygon Studio (2000, N64DD)
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| Miscellaneous
|
Mario's Bombs Away (1983, G&W) • Mario the Juggler (1991, G&W) • Yoshi's Safari (1993, SNES) • Undake30 Same Game (1995, SFC) • Mario's Game Gallery (1995, MS-DOS) • Mario's Picross (1995, GB) • Mario's Super Picross (1995, SFC) • Donkey Kong (slot machine) (1996, Arcade) • Picross 2 (1996, GB) • Excitebike: Bun Bun Mario Battle (1997, Satellaview) • Mario's FUNdamentals (1998, Windows) • Picross NP (1999-2000, SFC) • Super Mario Fushigi no Janjan Land (2003, Arcade) • Mario Pinball Land (2004, GBA) • Yakuman DS (2005, NDS) • Dance Dance Revolution: Mario Mix (2005, GCN)
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- Everyone
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