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Young MacDonald is a young farmer and the son of the well-known Old MacDonald.
In The Super Mario Bros. Super Show! episode "Flower Power", Mario, wanting to help Luigi, who has begun growing vegetables all over his body after eating spaghetti sauce filled with dehydrated vegetable seeds, calls Old MacDonald for help. As Young MacDonald explains when he arrived at Mario Brothers Plumbing, Old MacDonald is unavailable, attending a potato convention, so Young MacDonald visited Mario and Luigi in his place.
Brought over to Luigi, Young MacDonald begins to inspect him to see what is wrong with him, and after looking, says he has never seen anything like this before; asking Mario for some clippers, Young MacDonald decides to simply cut and pull the vegetables growing on Luigi off, which appears to work. After apparently curing Luigi, Young MacDonald is asked by Mario to take a look at the nearby vegetable garden growing in Mario and Luigi's spare bathtub. As Young MacDonald inspect Mario and Luigi's oddly shrieking carrots, Luigi suddenly grows more vegetables from his body and alerts Mario and Young MacDonald to this; seeing Luigi in this state, Young MacDonald tries to reassure him, saying that maybe he will get used to having vegetables grow from his body, much to Luigi's frustration.
Later, still wanting to help Luigi, Young MacDonald begins to try and research what was wrong with Luigi; as he researches, Young MacDonald manages to stop a fight that occurs between Mario and Luigi by saying he thinks he has found information on what is wrong with Luigi. Young MacDonald reveals to Mario and Luigi that Luigi is suffering from Veggieitis, a rare disease that occurs every three-hundred years in Brooklyn, and only when dehydrated vegetable seeds are eaten in spaghetti sauce. Young MacDonald also tells Luigi that to cure his Veggieitis, he needs to eat a rose, which will cause all the vegetables on his body to instantly fall off. Eating an old rose Mario gives him, Luigi is informed by Young MacDonald that eating a rose can cause Roseitis, which lasts a week and causes roses to grow from a person's ears.