From the Super Mario Wiki, the Mario encyclopedia
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Kamek Blocks are blocks that appear in Neo Bowser Castle in Mario & Luigi: Dream Team. They are white and have an image of Kamek's hat and glasses on them. When Kamek casts a spell on the doorways on one of the floors in the castle, the doorways will end up taking Mario and Luigi to a different area than intended. When the player finds a Kamek Block and hits it, a pair of symbols from Kamek's spell will be displayed on the map, showing them exactly where the two doorways lead to and from. Since the purpose of these blocks is to help the player navigate through the castle, hitting these are entirely optional.