From the Super Mario Wiki
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A wheelie is a technique that can only be used on a bike in Mario Kart Wii. They slightly increase the speed of the player's bike, but if they bump into an object or opponent while performing one, it cancels and the player loses speed. The player also drops any items deployed out. Also, the speed increase comes at the cost of reduced handling, and turning while performing a wheelie slows down the player substantially. Wheelies will fail if the player tries to perform one without moving, or if they are moving too slowly.
In Mario Kart 8 and Mario Kart 8 Deluxe, wheelies have been removed altogether, and cannot be performed by the player at will. However, during certain boosts, racers who are riding bikes will perform a purely cosmetic wheelie.
Depending on the player's controller, a wheelie is activated accordingly:
To stop them:
In addition, drifting can cancel a wheelie.