From the Super Mario Wiki, the Mario encyclopedia
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Handaconda is a giant black papery arm that appears as a boss in Paper Mario: The Origami King, fought in Bowser's Castle. Its name is a play on words on "hand" and "anaconda," a snake species that typically reside in South America.
During the first phase of the battle, Mario must use hammer attacks from the second-closest ring until Olivia is freed. If the Attack panel to be used is placed in the closest ring, Handaconda will simply push it away. If it is too far, Handaconda will bat away what is coming towards it; if the attack is a physical attack, it will use Asp Grasp to deal 10 damage to Mario.
When Handaconda attacks, if Mario is on the closest panel, it will use Bopperhead, dealing 31 damage. If not, it will instead use Cobra Throw, dealing 7-9 damage.
Additionally, due to the fact that Olivia is trapped, no Magic Circles can be used at this point in the battle. However, with each successful hit, Handaconda's grip is loosened. Once it is loose enough, Olivia is released, initiating the second phase of the battle.
Handaconda transforms the Magic Circles into Rock, Paper and Scissors icons, and all attack spaces disappear. When Mario stands on one of these spaces, he will activate the 1,000-Fold Arms and challenge Handaconda to a game of Rock, Paper, Scissors, using the symbol he is standing on. If both tie, Handaconda's hand will get bigger for the next turn only. If Handaconda wins, it will attack for 24 damage (36 if hand is large) and Mario must block. If Mario wins, he initiates a rush attack with the 1,000-Fold Arms. In addition, the closer Mario is to Handaconda during Rock Paper Scissors, the more damage the rush attack will deal per hit, but the less reaction time Mario gets to block. If Mario does not end up on an icon, Handaconda will use its phase one attack pattern.