From the Super Mario Wiki, the Mario encyclopedia
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A Tasty Tonic is an item in Paper Mario. The item is sold all over the world but is least expensive at Yoshi's Cabana for the price of two coins each; this is likely due to the large amount of poisonous enemies on Lavalava Island. A lot of Tasty Tonics are available throughout the game, in most item stores. A Tasty Tonic cures any Poison and/or shrinking done to Mario. They can be used outside of battle, but will have no effect because all status ailments go away at the end of a battle.
The Tasty Tonic reappears in Paper Mario: The Thousand-Year Door and serves the same purpose. It is sold in the item shop in Rogueport for three coins; it is also sold on the Excess Express for three coins.
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