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Lemons don't sell well anywhere and are largely only good for cooking. However, retrieving at least one is necessary for unlocking Dry Dry Ruins in the storyline as predicted by Merlon, as the way to earn the Pulse Stone (the only artifact capable of opening the Ruins) involves giving a Lemon to Sheek, who will then allow Mario to "meet" Moustafa (actually himself), owner of the Pulse Stone, by telling him to buy things in a specific order in Little Mouser's Shop. (If the player knows the order in advance, it is not necessary to use a Lemon to get this information, as Mario can do this directly.) Lemons are also good for making the Lemon Candy, which is useful in bribing the Anti Guy in Shy Guy's Toy Box.
In Donkey Kong Jungle Beat, Lemons appears at the end of every level in the Lemon Kingdom. After Donkey Kong reaches the end of that level, he munches through the whole lemon. This lemon is larger than Donkey Kong himself.
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