From the Super Mario Wiki
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Wolfenboss's main attack is to shoot energy balls at Wario. If he is hit, he'll be levitated out of the arena in a similar fashion to Bubble Wario and have to restart. To hit this floating fox, Wario has to wait until he throws a spike ball and wait until a Chestnut comes out of it. Then, Wario chooses the right place to hit him so he can bounce off the wall Wario is facing and hit Wolfenboss.
After Wolfenboss is hit two times, his spiked ball attack is harder to avoid, as it bounces around. If Wario is hit by the spiked ball, he'll become Puffy Wario and have to restart the battle. When hit three times, he falls and causes the cover blocking the way to the green chest to be removed.
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