Mario & Luigi can refer to:
- Mario and Luigi, the Mario Brothers.
- The Mario & Luigi series, the series including the following video games:
- Mario & Luigi: Superstar Saga, a 2003 game for the Game Boy Advance.
- Mario & Luigi: Partners in Time, the 2005 sequel to Superstar Saga, for the Nintendo DS.
- Mario & Luigi: Bowser's Inside Story, the 2009 sequel to Partners in Time, also for the Nintendo DS.
- Mario & Luigi: Dream Team, the 2013 sequel to Bowser's Inside Story, and the first in the series to be released for the Nintendo 3DS.
- Mario & Luigi: Paper Jam, a crossover with the Paper Mario series and the 2015 sequel to Dream Team, for the Nintendo 3DS.
- Mario & Luigi: Superstar Saga + Bowser's Minions, a 2017 remake of Mario & Luigi: Superstar Saga, for the Nintendo 3DS.
- Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey, a 2018 remake of Mario & Luigi: Bowser's Inside Story, for the Nintendo 3DS.
- M & L, an implied movie in the Yoshi Theater in Mario & Luigi: Superstar Saga.
- Mario & Luigi?!, a level in Bowser Jr.'s Journey.
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