From the Super Mario Wiki
Large Mildes are large Mildes that appear in Super Mario World 2: Yoshi's Island and Yoshi's Island: Super Mario Advance 3. They march around in a line and are very rare, only appearing as part of Marching Milde and in a few other levels. Like balloons, they pop if a Yoshi Ground Pounds on one. After a Yoshi pops one of these enemies, it splits, making four smaller Mildes. Large Mildes return in Yoshi's New Island.
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