Dr. Mario & Puzzle League

Dr. Mario & Puzzle League (also parsed Dr. Mario / Puzzle League, known as Dr. Mario & Panel de Pon in Japan) is a "2 in 1" game for the Game Boy Advance. Dr. Mario is an enhanced remake of the original Dr. Mario, using many of the graphics from Dr. Mario 64.

Puzzle League's name probably comes from Pokémon Puzzle League, a game based on Tetris Attack, which is in turn based on Panel de Pon. This version, however, is a very simple form of the game.

Gameplay
Dr. Mario mostly resembles the Nintendo 64 version, Dr. Mario 64. Like Dr. Wario, the unlockable minigame from WarioWare, Inc.: Mega Microgame$!, its bottle is 13 cells tall instead of the standard 16. Because of the smaller bottle size in this game, the amount of viruses for each level is different from the rest of the series:

Puzzle League is completely changed from the original Panel de Pon. The graphics closely resemble those of the GBA multiboot version from Nintendo Puzzle Collection. Both games have a Vertical Mode that can be unlocked, where one tilts the Game Boy Advance 90° counterclockwise to play, allowing for a higher resolution playing field. The controls using the D-pad is changed to account for the different view, though the controls for the other buttons remain the same. To unlock Vertical Mode for each mode, it is required to beat level 20 in Classic for Dr. Mario, and to beat level 6-5 in Line Mode for Puzzle League.

Both games have a Single-Pak and Multi-Pak multiplayer mode, and can also be used to upload a demo version to another Game Boy Advance using only one cart. The demo version of Dr. Mario features limited animation and an NES soundtrack. The demo version of Puzzle League features a small animal (Pupuri from Panel de Pon in Nintendo Puzzle Collection) on the side that calls out when blocks are cleared. The demo of Puzzle League is also the same demo from Nintendo Puzzle Collection.

Controls

 * Select options
 * Confirm
 * Cancel

Dr. Mario

 * (left/right): Move vitamin left/right
 * (down): Drop vitamin quickly
 * Rotate vitamin clockwise
 * Rotate vitamin counterclockwise
 * / : Vitamin ghost image On/Off
 * Pause

Vertical Mode

 * (up/down): Move vitamin left/right
 * (left): Drop vitamin quickly
 * (right): Rotate vitamin counterclockwise
 * Rotate vitamin clockwise
 * Rotate vitamin counterclockwise
 * Pause

Puzzle League

 * Move cursor
 * / : Switch blocks
 * / : Raise blocks
 * Pause
 * View hints in Puzzle mode

Promotion
A promotional tie-in browser game was released on the Nintendo Arcade website in 2005 called Dr. Mario Vitamin Toss.

Trivia

 * This game was released on the 20th anniversary of Super Mario Bros. in Japan.
 * This is the last game in the Dr. Mario series to have a physical release. Every game released after it was only made available as a digital download.

Reference
Dr. Mario & Puzzle League