Dr. Mario 64

Dr. Mario 64 is a puzzle game developed by Nintendo and released for the Nintendo 64. It was rereleased along with Tetris Attack and Yoshi's Cookie in a GameCube game called Nintendo Puzzle Collection in 2003, which was never released outside Japan.

Gameplay
Dr. Mario 64 plays the same as its pre­de­cess­ors for the most part. Dr. Mario throws Mega&shy;vita&shy;mins into a jar full of Viruses, and lining up a combination of Viruses and Megavitamins (four at minimum), they disappear. There are three types of Viruses - the Red Virus (Fever), the Blue Virus (Chill) and the Yellow Virus (Weird), with a Megavitamin color designed to defeat them. Dr Mario 64 features many different modes of play. The player uses the D-Pad to toggle with the different modes he wishes to select. The first one is Classic mode, where Dr. Mario is playable like he was originally. In the second mode of play, Story mode, Dr. Mario or Wario must track down the stolen Megavitamins. This mode only has versus matches against computers. The third mode allows practice against a computer player, where any character found in Story mode can be selected. The fourth game mode is Flash mode, where only the clearing of flashing Viruses counts. The fifth game mode is Marathon mode, which is basically an endless mode (the Viruses never stop coming out of the bottom of the jar). The sixth game mode is Score Attack mode, where there are only three minutes to get both a high score and clear all of the viruses. Multiplayer mode now supports up to four players, which adds a mode allowing four players to play on two teams.

Plot
Unlike past Dr. Mario games, this game has a plotline. It's flu season, and it's Dr. Mario's duty to use his Megavitamins to heal the infermities of the citizens of the land. However, Wario attempts to steal the Megavitamins. He belives that if he has them, he will be rich. Before he could do so, Mad Scienstein steals the Megavitamins. Dr. Mario runs into Wario, believing he has the Megavitamins, and they duel. Afterwards, and they both go after Mad Scienstein. Throughout their adventure, both of them meet up with many creatures, all of them being villains taken from Wario Land 3. In the end, it is revealed Mad Scienstein stole the Megavitamins for the diabolical Rudy the Clown, who wished to cure his cold. Dr. Mario defeated Rudy, took back his trusty Megavitamins, and made Rudy happy by curing his cold.

Characters

 * Dr. Mario
 * Wario
 * Spearhead
 * Webber
 * Silky
 * Appleby
 * Jellybob
 * Octo
 * Helio
 * Lumpy
 * Hammer-Bot
 * Mad Scienstein
 * Rudy the Clown
 * Metal Mario (unlockable)
 * Vampire Wario (unlockable)

References to Other Games

 *  Dr. Mario- The basic formula for the Dr. Mario series is carried on from this game.
 * Super Mario 64- Metal Mario (a secret unlockable character) is a power-up from this game.
 * Wario Land 3- All character's apart from Dr. Mario and Metal Mario are from this game.