Dr. Mario: Miracle Cure

Dr. Mario: Miracle Cure is the seventh main installment in the Dr. Mario series, released for Nintendo 3DS in 2015. It was the final title in the Mario franchise to be released with Satoru Iwata as its executive producer before his death on July 11, 2015 (discounting posthumously-released titles).

Gameplay
A new feature included only in Dr. Mario mode is the titular Miracle Cure. A Miracle Cure can be obtained by filling up a gauge that sits beside the bottle, and each Miracle Cure comes in the form of an item with a unique effect. Most Miracle Cures have a beneficial effect for the user, but certain Miracle Cures can only be found in vs. battles, where they can disrupt the opponent. When Miracle Cure is enabled, there is a gauge with one of the listed Miracle Cures below, and once it is filled, the next piece will be the designated Miracle Cure while the next capsule will be put on hold until the Miracle Cure dropped. The gauge will gradually fill as time passes, and it will also fill when a capsule match is made, where it fills up faster the more viruses and/or capsules are cleared. Once the Miracle Cure is placed in the stage, the gauge will be empty and another Miracle Cure will be shown at the top of the gauge.

The single player mode consists of two types: Miracle Cure Laboratory, which is a collection of pre-designed stages, and Custom Clinic, which the player can configure the course settings and play. In Custom Clinic, there are three modes to choose from: Dr. Mario, which is the series' standard gameplay; Dr. Luigi, which is the "Operation L" gameplay mode as seen in Dr. Luigi; and Virus Buster (Germ Buster in UK), in which players must drag continuously falling capsules onto the Viruses. For the Dr. Mario and Dr. Luigi modes, Miracle Cure can be enabled or disabled, which changes if it is available in Vs. CPU mode; however, Classic is only available if Miracle Cure is off, whereas Endless is only available if Miracle Cure is on.

In Classic mode and Vs. CPU mode, the player can choose the starting level and speed in which the capsules fall. In Vs. CPU mode, the speed in which the capsules fall is also correlated to the CPU's difficulty, where it is Easy difficulty at Slow speed, Normal difficulty at Med (medium) speed, and Hard difficulty at High speed. For the Dr. Luigi's modes, selecting Slow and Med speeds will cause the L-capsules to have three pieces in one color and one in another, while selecting the Fast speed will cause the L-capsules to have two pieces in one color and two in another, both colors in one full capsule each. For Virus Buster, the player can choose the starting level and the difficulty, which is based on not only the speed in which capsules drop but also how soon the amount of capsules added to the stage are increased. In Virus Buster only, the starting stage can go past level 20 as long as the player reached it, and each difficulty has individual maximum levels. In both Classic mode and Virus Buster mode, the score that the player obtained in the stage is not saved between levels, meaning that after eliminating all the viruses and proceeding to the next stage, the score is reset to zero, although the high score is still tracked.

For Endless mode, there are no settings to select, meaning that just selecting Endless starts the game. There are no levels in Endless, so the player will keep playing in the same stage for as long as possible. In regards to the Dr. Luigi mode, the two capsules in each L-capsule piece are each like-colored, similar to when selecting the Fast capsule speed. A minor difference is that in Endless, viruses will stay in the status screen even though all viruses of that color would be currently eliminated, which is unlike Dr. Mario 64's endless mode where the virus of that color will be gone if all matching viruses are currently absent (they will reappear if that colored virus appear again). At certain points in Endless, the objects in the stage will be pushed upwards from the bottom, which the player will be informed ahead of time based on a countdown and a number (between 1 and 4) of rows at the top. The countdown is based on the amount of capsule or miracle cures placed on the stage. Also, if all viruses in the stage are eliminated, the stage will be pushed up automatically to provide new viruses. If an object goes past the top due to being pushed, the game ends.

Unlike past Dr. Mario games, the music that plays in the stage cannot be chosen, nor can it be turned off. In fact, the music could change between levels for Classic mode. The music will be randomly chosen between Fever and Chill in the Dr. Mario mode, the music is between Drowsy and Dizzy for the Dr. Luigi mode, while the music is between a slower and calmer version of either Fever or Chill in Virus Buster. New to this game is the ability to rotate capsules 180 degrees if a capsule is currently in a narrow gap.

After every 30 minutes, there will be a message in which the player is advised to take a break.

Multiplayer
This game features online and local multiplayer. When playing locally, there are two options: Local Play, which allows two players with a copy of this game to play, and Download Play, in which the other player must connect to the system via 3DS Download Play to play with the player who owns the game. For the latter option, only the host can set up the game settings while the other player has to wait. In the multiplayer mode, there are three options: Dr. Mario, Dr. Luigi, and Virus Buster. For the former two, Miracle Cure can be enabled or disabled, and there are options on selecting the virus level and capsule drop speed; also, unlike the Vs. CPU mode, neither player is represented by Dr. Mario or Dr. Luigi.

In the multiplayer's Virus Buster, there are two modes: Battle and Co-op. For Battle, the two players compete with each other in Virus Buster to clear their side of the board the fastest, and if one of the players won three times out of five, indicated by the amount of stars earned, they win. Unlike Classic modes, performing a combo does not disrupt the opponent. The Level and the Difficulty are also random, meaning that respectively, the starting amount of viruses and the intervals in which capsules fall are different each time a match is played. For Co-op, both players are tasked to eliminate all the viruses by working together. Each player can only drag one capsule at a time, and a capsule cannot be dragged by both players. In terms of difficulty, the amount of capsules the player starts with is increased from the start compared to the other Virus Buster modes. For the virus level in Co-op, the amount of viruses in which the player starts with are 19 viruses in Easy, 29 in Normal, and 39 in Hard. Co-op also keeps track of the amount of time and the amount of viruses each player eliminated.

Miracle cures
This is a list of miracle cures that can appear when Miracle Cure is enabled. Much like capsules, miracle cures that are not exclusive to vs. battles are affected by gravity, meaning that any miracle cures that appear in the beginning of the stage will drop if any viruses mid-air are eliminated below them.

For miracle cures that appear exclusively in vs. battles, all of them are indicated by a sphere with an exclamation mark, in which it could be any one of the three available miracle cures. Those miracle cures will instantly activate as soon as the gauge is full, and will affect the opponent where they will take effect after the opponent places their current capsule, after which the actual effect is revealed. Each of them lasts for for a short time, where their expiry are indicated by when the appropriate icon blinks and a blinking sound is played.

Training

 * 1: Intro to Dr. Mario
 * 2: Intro to Dr. Luigi
 * 3: Advanced L-Capsules
 * 4: Blasting Capsules
 * 5: Z-Blasting Capsules
 * 6: Blasting Viruses
 * 7: Zap Attacks
 * 8: Explosive Treatments
 * 9: Miracle Cure Combos
 * 10: Shocking Sabotages

Basic

 * 1: On Call with Dr. Mario
 * 2: On Call with Dr. Luigi
 * 3: Mushroom Medic
 * 4: Fire Flower First Aid
 * 5: Efficient Treatment
 * 6: Chain Training
 * 7: Step It Up
 * 8: Rainbow Riot
 * 9: Step It Up 2
 * 10: Rainy-Day Remedy
 * 11: Head-to-Head Challenge
 * 12: Head-to-Head Challenge 2
 * 13: One-Move Medication
 * 14: Four-Move Medication
 * 15: Rapid Remedy
 * 16: Pot Luck
 * 17: Rapid Remedy 2
 * 18: Two-Move Medication
 * 19: Be the Best!
 * 20: Be the Best! 2

Advanced

 * 1: Coin Collector
 * 2: Bottled Bottle
 * 3: Grin and Bear It
 * 4: Mining for Miracles
 * 5: Virus Valley
 * 6: Harmonic Healing
 * 7: Superstar Science
 * 8: Vertical Zapper Zinger
 * 9: Exploderama
 * 10: Musical Mayhem
 * 11: P Switch Pushover
 * 12: Rainbow Road
 * 13: Three-Move Medication
 * 14: Zap to Zilch
 * 15: A Heartfelt Battle
 * 16: Vertical Zapper Dropper
 * 17: Strawberry Crop
 * 18: Leave No Leftovers
 * 19: Miraculous Recovery
 * 20: Arch Nemesis
 * 21: Butterfly Buster
 * 22: The Hidden Heart
 * 23: Ten-Chain Champ
 * 24: Buried Treasure
 * 25: Speedy Treatment
 * 26: Controlled Demolition
 * 27: Zap the Left, Blast the Rest
 * 28: Stair Builder
 * 29: Red and Blue Maze
 * 30: Royal Radiance

Trivia

 * In South Korea, this game was released as an exclusive bundle game of Mario & Luigi: Paper Jam. It was only downloadable from May 26 to August 31, 2016.
 * This game's 3D effect is limited to the title screen, as every other part of this game is strictly in 2D, even with the 3D slider on.