Lava Dome

Lava Dome is the fifth floor in Mario vs. Donkey Kong 2: March of the Minis. This floor is very dark, with volcanoes pictured in the background. The floor bears a significant resemblance to worlds concerning Bowser found in various other Mario games. Lava is a common hazard in this floor, often featured in the foreground, along with fire-based elements such as Podoboos and Fire Bars. Jetpack Guys and Crash Kongs can also be seen here. The music is a remix of the Bowser's Castle theme from the original Super Mario Bros.

The battle with Donkey Kong is almost identical to the first battle in Mushroom Mayhem. However he will also drop Bubbles along with Barrels and Weights. If a mini comes in contact with a Bubble. They will become immune to all projectiles Donkey Kong drops down at them. They lose this effect if the mini is either shot out of the cannon or is hit by one of Donkey Kong's projectiles. Once defeated, he flees to Toadstool Castle.

Enemies

 * Jetpack Guys
 * Podoboos
 * Circus Kongs
 * Thwomp
 * Fires
 * Mini Shy Guys
 * Mini Bob-ombs (appear in minigame)
 * Crash Kongs
 * Cool Kongs
 * Fire Bars
 * Donkey Kong (boss)

Lava Fountain
In the vast lava hazards in this game, there is a platform that moves back and forth. Often, Lava Fountains occur underneath the platform shooting it upwards through the air, allowing Mini Marios to move to another platform. Sometimes Lava Fountains can shoot to multiple heights.

Fire Blocks
From levels starting with 5-5, Fire Blocks will start appearing across levels. They work like Pink Blocks but when removed, the background starts flashing yellow and the player can place a Fire on a wood platform and burn it to access previously inaccessible areas.