Poison

Poison could refer to:
 * Poison, a hazardous liquid mostly found in the Super Mario series.
 * Poison, a negative status ailment that slowly drains HP appearing in many Super Mario RPGs.
 * Poison, a special attack that induces the Poison status ailment in the game Super Mario RPG: Legend of the Seven Stars.
 * Skull, a Normal Item in Wario Blast: Featuring Bomberman! sometimes referred to as "Poison" in the Bomberman series.